STMN2 and TRPC5

Number of citations of the paper that reports this interaction (PubMedID 12858178)
117

Data Source:
HPRD (in vivo, two hybrid)

		STMN2	TRPC5
Description		stathmin 2	transient receptor potential cation channel subfamily C member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Membrane Lamellipodium Growth Cone Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Membrane Raft
	Molecular Function	Protein Binding Tubulin Binding Calcium-dependent Protein Binding	Actin Binding Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Neuron Projection Development Cellular Response To Nerve Growth Factor Stimulus	Calcium Ion Transport Manganese Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Peptidyl-threonine Phosphorylation Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Phosphatidylserine Exposure On Apoptotic Cell Surface Regulation Of Membrane Hyperpolarization
Pathways		RND1 GTPase cycle	TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS		Creutzfeldt-Jakob disease ( 19081515) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Smoking behavior ( 19247474)
Interacting Genes		28 interacting genes: CCDC85A CCHCR1 CDC42 CDK1 CEP70 CTNNA3 EEF1A1 ERBB2 FAM90A1 FANCC GPRASP1 GPRASP2 MAPK10 MAPK3 MBD3 NGFR NTAQ1 PRKACA PSMB1 PSMC1 RGS20 RGS6 SESTD1 TEX11 TFCP2 TRPC5 TXLNA UBE2I	10 interacting genes: DRD2 ENKUR ITPR3 MX1 PLS3 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4
Entrez ID		11075	7224
HPRD ID		09003	02273
Ensembl ID		ENSG00000104435	ENSG00000072315
Uniprot IDs		Q93045	Q9UL62
PDB IDs			6YSN
Enriched GO Terms of Interacting Partners?
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