TRAPPC10 and UBE2G2

		TRAPPC10	UBE2G2
Description		trafficking protein particle complex subunit 10	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol TRAPP Complex TRAPPII Protein Complex	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Intra-Golgi Vesicle-mediated Transport Early Endosome To Golgi Transport	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301)
Interacting Genes		15 interacting genes: GET1 SLC19A1 SUMO3 TFF1 TFF2 TFF3 TMPRSS2 TRAPPC12 TRAPPC3L TRAPPC6A TRAPPC6B TRAPPC8 TRPM2 U2AF1 UBE2G2	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		7109	7327
HPRD ID		03656	04387
Ensembl ID		ENSG00000160218	ENSG00000184787
Uniprot IDs		P48553	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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