UBE2G2 and TMEM45B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		UBE2G2	TMEM45B
Description		ubiquitin conjugating enzyme E2 G2	transmembrane protein 45B
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301)	Breast cancer ( 22383897) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Obsessive-compulsive traits ( 33531474) Serum metabolite levels ( 33031748) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Type 2 diabetes ( 22238593)
Interacting Genes		41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	41 interacting genes: ANKRD46 APOD APOL2 AQP1 BMP10 C3orf52 C4orf3 CACNG1 CDS2 CYB561D2 DOLK FAM3C FKBP8 GIMAP1 INSIG2 LAT NSG1 PLN PLP1 PLPP4 SEC22A SEC23A SMAGP SMIM1 SNORC SYNGR1 TINAG TMEM128 TMEM218 TMEM229B TMEM243 TMEM254 TMEM60 TMEM97 TNFRSF10C TREX1 TSPAN33 UBE2G2 UPK1B VAMP5 VKORC1
Entrez ID		7327	120224
HPRD ID		04387	14020
Ensembl ID		ENSG00000184787	ENSG00000151715
Uniprot IDs		P60604	Q96B21
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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