ACTC1 and TWF1

Number of citations of the paper that reports this interaction (PubMedID 12207032)
20

Data Source:
HPRD (in vivo)

		ACTC1	TWF1
Description		actin alpha cardiac muscle 1	twinfilin actin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Actin Filament Focal Adhesion Membrane Sarcomere Lamellipodium Filopodium I Band Cell Body Extracellular Exosome Blood Microparticle	Nucleolus Cytoplasm Cytosol Actin Filament Cell-cell Junction Focal Adhesion Actin Cytoskeleton Myofibril Filopodium Ruffle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Microfilament Motor Activity ATP Binding Myosin Binding	Actin Binding Actin Monomer Binding Protein Tyrosine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Cadherin Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Actin Filament-based Movement Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Regulation Of Lamellipodium Assembly Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Neuron Projection Development Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Sequestering Of Actin Monomers Regulation Of Actin Phosphorylation Barbed-end Actin Filament Capping
Pathways		Striated Muscle Contraction RHOA GTPase cycle RHOB GTPase cycle	RHOBTB2 GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Axial length ( 24144296) Refractive error ( 32231278 20835239)	Inflammatory bowel disease ( 27569725)
Interacting Genes		42 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG ASH2L BCL11A C1QTNF9 CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK OGT PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	5 interacting genes: ACTC1 APP BMPR2 CSNK2B FBXO25
Entrez ID		70	5756
HPRD ID		00015	10174
Ensembl ID		ENSG00000159251	ENSG00000151239
Uniprot IDs		B3KPP5 P68032	Q12792
PDB IDs			7CCC
Enriched GO Terms of Interacting Partners?
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