ACTC1 and MPC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ACTC1	MPC1
Description		actin alpha cardiac muscle 1	mitochondrial pyruvate carrier 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Actin Filament Focal Adhesion Membrane Sarcomere Lamellipodium Filopodium I Band Cell Body Extracellular Exosome Blood Microparticle	Mitochondrion Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Microfilament Motor Activity ATP Binding Myosin Binding	Molecular_function Protein Binding Pyruvate Transmembrane Transporter Activity
	Biological Process	Actin Filament Organization Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Actin Filament-based Movement Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Mitochondrial Pyruvate Transmembrane Transport Biological_process
Pathways		Striated Muscle Contraction RHOA GTPase cycle RHOB GTPase cycle	Pyruvate metabolism
Drugs
Diseases
GWAS		Axial length ( 24144296) Refractive error ( 32231278 20835239)
Interacting Genes		42 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG ASH2L BCL11A C1QTNF9 CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK OGT PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	4 interacting genes: ACTC1 GABARAP MAGED1 MPC2
Entrez ID		70	51660
HPRD ID		00015	07091
Ensembl ID		ENSG00000159251	ENSG00000060762
Uniprot IDs		B3KPP5 P68032	Q5TI65 Q9Y5U8
PDB IDs
Enriched GO Terms of Interacting Partners?
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