STK3 and PHAX

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		STK3	PHAX
Description		serine/threonine kinase 3	phosphorylated adaptor for RNA export
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity Protein Serine Kinase Activity	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding
	Biological Process	Neural Tube Formation Endocardium Development Protein Phosphorylation Apoptotic Process Signal Transduction Central Nervous System Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Binding Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of MAPK Cascade Positive Regulation Of Fat Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of Organ Growth Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Protein Tetramerization Positive Regulation Of Protein Kinase B Signaling Primitive Hemopoiesis Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Hepatocyte Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	SnRNA Export From Nucleus Protein Transport RNA Stabilization
Pathways		Signaling by Hippo	snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs		Fostamatinib
Diseases
GWAS		Depressive symptom improvement ( 30468137) Heel bone mineral density ( 30598549) Rosacea symptom severity ( 29771307) Suicide behavior ( 26079190)	Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)
Interacting Genes		42 interacting genes: AKT1 CASP3 CDK1 CNKSR1 CPNE1 DDAH2 EIF4EBP1 FAM9B GABARAP GABARAPL1 GAD1 GBP2 GMCL1 HSPE1 KEAP1 KHSRP LATS1 LATS2 LRRK2 MAP1LC3B MAP1LC3C MARK2 MBP MOB1B MOB3B MOB4 MPP1 OGT ORM2 PEX19 PHAX PLK1 QARS1 RAF1 RASSF4 SAV1 SLMAP SNIP1 SULT2A1 TFPT TRAF1 ZC3H7A	19 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 ITIH1 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 STK3 TBCA TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		6788	51808
HPRD ID		05433	15122
Ensembl ID		ENSG00000104375	ENSG00000164902
Uniprot IDs		A0A087WZ06 A0A384MR07 Q13188	Q9H814
PDB IDs		3WWS 4HKD 4L0N 4LG4 4LGD 4OH9 5BRM 5DH3 6AO5 6AR2	2XC7
Enriched GO Terms of Interacting Partners?
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