SUMO3 and TRAPPC10

		SUMO3	TRAPPC10
Description		small ubiquitin like modifier 3	trafficking protein particle complex subunit 10
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body	Cytosol TRAPP Complex TRAPPII Protein Complex
	Molecular Function	Protein Binding Protein Tag Ubiquitin-like Protein Ligase Binding	Protein Binding
	Biological Process	Protein Sumoylation Negative Regulation Of DNA Binding Regulation Of Protein Localization To Nucleus	Intra-Golgi Vesicle-mediated Transport Early Endosome To Golgi Transport
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Delirium ( 29631748)
Interacting Genes		55 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 MORC3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TRAPPC10 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496	15 interacting genes: GET1 SLC19A1 SUMO3 TFF1 TFF2 TFF3 TMPRSS2 TRAPPC12 TRAPPC3L TRAPPC6A TRAPPC6B TRAPPC8 TRPM2 U2AF1 UBE2G2
Entrez ID		6612	7109
HPRD ID		03754	03656
Ensembl ID		ENSG00000184900	ENSG00000160218
Uniprot IDs		P55854	P48553
PDB IDs		1U4A 2IO1 2MP2 6K5R 6NNQ
Enriched GO Terms of Interacting Partners?
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