SFTPD and PLXNA3

		SFTPD	PLXNA3
Description		surfactant protein D	plexin A3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endocytic Vesicle Clathrin-coated Endocytic Vesicle	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Carbohydrate Binding	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity
	Biological Process	Regulation Of Cytokine Production Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Induction Of Bacterial Agglutination Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Negative Regulation By Host Of Symbiont Catalytic Activity Reactive Oxygen Species Metabolic Process Regulation Of Adhesion Of Symbiont To Host Epithelial Cell	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Hippocampus Development Branchiomotor Neuron Axon Guidance Pyramidal Neuron Development Regulation Of Cell Migration Regulation Of GTPase Activity Negative Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Axonogenesis Negative Chemotaxis Positive Regulation Of Cytoskeleton Organization Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension
Pathways		Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling
Drugs		Beta-D-Glucose
Diseases
GWAS		Chronic obstructive pulmonary disease ( 28166215 30804561 33909500) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		12 interacting genes: CCN1 DCN DMBT1 GPA33 KCNMA1 LBR MFAP4 PLAU PLXNA3 RBX1 SFTPA1 SMR3B	9 interacting genes: CSNK2B MAPK8IP2 MTDH PPP2CB SFTPD SMN1 TK1 TRIM55 TRIM63
Entrez ID		6441	55558
HPRD ID		01522	02062
Ensembl ID		ENSG00000133661	ENSG00000130827
Uniprot IDs		P35247	P51805
PDB IDs		1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?
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