SFTPD and DMBT1

Number of citations of the paper that reports this interaction (PubMedID 9153228)
58

Data Source:
BioGRID (biochemical, pull down, pull down)
HPRD (in vitro)

		SFTPD	DMBT1
Description		surfactant protein D	deleted in malignant brain tumors 1
Image
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endocytic Vesicle Clathrin-coated Endocytic Vesicle	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Extracellular Matrix Binding
	Biological Process	Regulation Of Cytokine Production Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Induction Of Bacterial Agglutination Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Negative Regulation By Host Of Symbiont Catalytic Activity Reactive Oxygen Species Metabolic Process Regulation Of Adhesion Of Symbiont To Host Epithelial Cell	Endocytosis Defense Response Protein Transport Epithelial Cell Differentiation Detection Of Bacterial Lipoprotein Induction Of Bacterial Agglutination Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus
Pathways		Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4	Surfactant metabolism
Drugs		Beta-D-Glucose
Diseases
GWAS		Chronic obstructive pulmonary disease ( 28166215 30804561 33909500) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 30423114 24390342)	Iris heterochromicity ( 30895295)
Interacting Genes		12 interacting genes: CCN1 DCN DMBT1 GPA33 KCNMA1 LBR MFAP4 PLAU PLXNA3 RBX1 SFTPA1 SMR3B	7 interacting genes: GNB3 MEAF6 MRPS6 PRSS2 SELENBP1 SFTPA1 SFTPD
Entrez ID		6441	1755
HPRD ID		01522	03575
Ensembl ID		ENSG00000133661	ENSG00000187908
Uniprot IDs		P35247	A0A590UJ76 Q9UGM3
PDB IDs		1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS	6SA4 6SA5 6SAN
Enriched GO Terms of Interacting Partners?
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