RAP2A and MAP4K4

  • Number of citations of the paper that reports this interaction (PubMedID 14966141)
  • 45
  • Data Source:
  • HPRD (two hybrid)

RAP2A

MAP4K4

Description RAP2A, member of RAS oncogene family mitogen-activated protein kinase kinase kinase kinase 4
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Peripheral artery disease ( 26488411)
  • Alzheimer's disease ( 30636644)
  • Asthma ( 31619474)
  • Asthma (time to onset) ( 27130862)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • White blood cell count ( 32888494)
Interacting Genes 34 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B CDK4 EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D IRS2 MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK 18 interacting genes: BRCA1 CASP8 DOK1 GBP3 H2BC21 ITGB1 KIF26B KIF5A MAP3K7 NCK1 NME7 PPP1CA PPP1CC PRKCE RAP2A RASA1 SLC9A1 TBPL2
Entrez ID 5911 9448
HPRD ID 01547 05235
Ensembl ID ENSG00000125249 ENSG00000071054
Uniprot IDs P10114 B7Z3V5 O95819 V9HWH3
PDB IDs 1KAO 2RAP 3RAP 4OBO 4OBP 4OBQ 4RVT 4U3Y 4U3Z 4U40 4U41 4U42 4U43 4U44 4U45 4ZK5 4ZP5 5DI1 5J95 5W5Q
Enriched GO Terms of Interacting Partners?
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