RAP2A and RAPGEF4

  • Number of citations of the paper that reports this interaction (PubMedID 10777494)
  • 122
  • Data Source:
  • BioGRID (enzymatic study)

RAP2A

RAPGEF4

Description RAP2A, member of RAS oncogene family Rap guanine nucleotide exchange factor 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Peripheral artery disease ( 26488411)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Fasting blood glucose ( 33842983)
  • Fasting plasma glucose ( 25187374)
  • GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273)
  • HDL cholesterol levels ( 32203549)
  • Hippocampal volume ( 25625606)
  • Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes 34 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B CDK4 EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D IRS2 MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK 13 interacting genes: ATXN1 BMERB1 DEF6 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A
Entrez ID 5911 11069
HPRD ID 01547 06929
Ensembl ID ENSG00000125249 ENSG00000091428
Uniprot IDs P10114 B7Z278 Q8WZA2
PDB IDs 1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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