PAK6 and TPD52L1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PAK6	TPD52L1
Description		p21 (RAC1) activated kinase 6	TPD52 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Cytosol Cell Junction	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Protein Serine Kinase Activity	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Learning Memory Locomotory Behavior Intracellular Signal Transduction Regulation Of MAPK Cascade Neuron Projection Arborization Neuron Projection Extension	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Activation of RAC1 CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOH GTPase cycle RHOV GTPase cycle	Golgi Associated Vesicle Biogenesis
Drugs		Fostamatinib
Diseases
GWAS		Obesity-related traits ( 23251661) Schizophrenia ( 25056061 29483656) Weight gain in amisulpride-treated first-episode psychosis ( 32126890)	Night sleep phenotypes ( 27126917)
Interacting Genes		28 interacting genes: APP AR CACNA1H CDC42 CDIN1 CDK1 DAPK1 DLL4 ESR1 FBXO7 GJD2 HSF2BP KNL1 LIMK1 LRRK1 MAPK14 MDM2 NEK6 PTPRD RAC1 RHOJ RHOV SEMA3B SNX2 SP3 SPG11 SUMO2 TPD52L1	15 interacting genes: ABL2 DAPK1 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 PBX3 TPD52 TPD52L2 TPD52L3 YAE1 YWHAB YWHAZ
Entrez ID		56924	7164
HPRD ID		06426	07236
Ensembl ID		ENSG00000137843	ENSG00000111907
Uniprot IDs		A0A024R9Q4 Q9NQU5	E9PNK6 E9PPQ1 J3KNE7 Q15730 Q16890
PDB IDs		2C30 2ODB 4KS7 4KS8 6QDR 6QDS
Enriched GO Terms of Interacting Partners?
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