ATR and CHEK2

  • Number of citations of the paper that reports this interaction (PubMedID 10973490)
  • 271
  • Data Source:
  • BioGRID (genetic interference)
  • HPRD (in vitro, in vivo)

ATR

CHEK2

Description ATR serine/threonine kinase checkpoint kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 50 interacting genes: AATF ABL1 AP1B1 AP3B1 ARHGEF1 ATM BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CHUK CLSPN CREB1 DCAF1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 ETV1 FANCA FANCD2 FANCI FLT1 H2AX KDR LIG4 MCM2 MCPH1 MRE11 MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R3A RAD17 RASSF1 RHEB TP53 TREX1 UPF1 XPA XRCC5 85 interacting genes: AATF APP ARHGAP1 ASF1A ATM ATR BAALC BEX1 BRCA1 BRCA2 CCL5 CDC25A CDC25C CDH13 CDK11B CDKN1A CRKL CYP17A1 DAPK3 DBF4 DIRAS3 E2F1 ELAVL1 ENO1 ERCC6 FHL1 FHL3 FOXM1 FUS GNAS GRK3 HMGN1 HOXC6 ITIH5 KLK7 KLK9 KPNA2 LATS2 LYPD3 MAPT MDC1 MDM2 MDM4 MN1 MRC1 MSH2 MUS81 NBN NR4A1 NSD3 PLK1 PLK3 POLR2L PPM1D PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRDM14 PRKDC PRMT2 PSMC3IP PSME3 RAD9A RCHY1 REV3L RHOBTB2 RNF8 SIAH2 SLC25A6 SRPK1 SRPK2 ST14 STMN1 STRAP SUSD2 TLR3 TP53 TSSK1B USP39 VHL
Entrez ID 545 11200
HPRD ID 08369 05084
Ensembl ID ENSG00000175054 ENSG00000183765
Uniprot IDs Q13535 O96017
PDB IDs 5YZ0 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK
Enriched GO Terms of Interacting Partners?
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