ATR and RHEB

  • Number of citations of the paper that reports this interaction (PubMedID 15854902)
  • 391
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

ATR

RHEB

Description ATR serine/threonine kinase Ras homolog, mTORC1 binding
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Metabolite levels ( 23823483)
Interacting Genes 50 interacting genes: AATF ABL1 AP1B1 AP3B1 ARHGEF1 ATM BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CHUK CLSPN CREB1 DCAF1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 ETV1 FANCA FANCD2 FANCI FLT1 H2AX KDR LIG4 MCM2 MCPH1 MRE11 MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R3A RAD17 RASSF1 RHEB TP53 TREX1 UPF1 XPA XRCC5 35 interacting genes: A2M APOE APPBP2 ARIH2 ATM ATR BNIP3 BNIP3L BRAF CENPE CREB3 ECSIT FKBP8 HTT MAPK15 MTOR NCAM1 NOS3 PDE6D PIGB PLD1 PPP1R3C PSEN1 PSEN2 PTPRN2 RABAC1 RAF1 RNF152 RPS6KB1 RPTOR TRIM55 TRIM63 TSC1 TSC2 USP4
Entrez ID 545 6009
HPRD ID 08369 03188
Ensembl ID ENSG00000175054 ENSG00000106615
Uniprot IDs Q13535 A0A090N900 Q15382
PDB IDs 5YZ0 1XTQ 1XTR 1XTS 3SEA 3T5G 5YXH 6BCU 6BSX 6BT0 7BTA 7BTC 7BTD
Enriched GO Terms of Interacting Partners?
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