CHEK2 and PRKDC

  • Number of citations of the paper that reports this interaction (PubMedID 17171639)
  • 50
  • Data Source:
  • BioGRID (enzymatic study, enzymatic study)

CHEK2

PRKDC

Description checkpoint kinase 2 protein kinase, DNA-activated, catalytic subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 85 interacting genes: AATF APP ARHGAP1 ASF1A ATM ATR BAALC BEX1 BRCA1 BRCA2 CCL5 CDC25A CDC25C CDH13 CDK11B CDKN1A CRKL CYP17A1 DAPK3 DBF4 DIRAS3 E2F1 ELAVL1 ENO1 ERCC6 FHL1 FHL3 FOXM1 FUS GNAS GRK3 HMGN1 HOXC6 ITIH5 KLK7 KLK9 KPNA2 LATS2 LYPD3 MAPT MDC1 MDM2 MDM4 MN1 MRC1 MSH2 MUS81 NBN NR4A1 NSD3 PLK1 PLK3 POLR2L PPM1D PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRDM14 PRKDC PRMT2 PSMC3IP PSME3 RAD9A RCHY1 REV3L RHOBTB2 RNF8 SIAH2 SLC25A6 SRPK1 SRPK2 ST14 STMN1 STRAP SUSD2 TLR3 TP53 TSSK1B USP39 VHL 91 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C DUX4 E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB IKBKG ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD PTEN RAD17 RASSF1 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A
Entrez ID 11200 5591
HPRD ID 05084 02941
Ensembl ID ENSG00000183765 ENSG00000253729
Uniprot IDs O96017 P78527
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK 5LUQ 5W1R 5Y3R 6ZFP 6ZH2 6ZH4 6ZH6 6ZH8 6ZHA 6ZHE 7K0Y 7K10 7K11 7K19 7K1B 7K1J 7K1K 7K1N
Enriched GO Terms of Interacting Partners?
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