PPIL3 and TAB3

Number of citations of the paper that reports this interaction (PubMedID 30348973)
2

Data Source:
BioGRID (pull down, unspecified method)

		PPIL3	TAB3
Description		peptidylprolyl isomerase like 3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Catalytic Step 2 Spliceosome	Cytosol Plasma Membrane Endosome Membrane Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	Protein Binding Zinc Ion Binding Ubiquitin Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Negative Regulation Of Autophagy Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		mRNA Splicing - Major Pathway	NOD1/2 Signaling Pathway FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		16 interacting genes: ALS2 CDK11B CENATAC MAIP1 MOB4 NOP58 NUP107 PCBP1 SHARPIN SLU7 SPATS2L SRPK1 STRADB TAB2 TAB3 WDR12	10 interacting genes: CEP57L1 IKBKG MAP3K7CL OGT PIN1 PPIL3 STAT3 TAB1 TRAF2 TRAF6
Entrez ID		53938	257397
HPRD ID		15163	06738
Ensembl ID		ENSG00000240344	ENSG00000157625
Uniprot IDs		A0A024R3V4 A0A0S2Z5A8 Q9H2H8	Q8N5C8
PDB IDs		1XYH 2OJU 2OK3
Enriched GO Terms of Interacting Partners?
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