CXCR5 and TLK1

		CXCR5	TLK1
Description		C-X-C motif chemokine receptor 5	tousled like kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Nucleus Nucleoplasm
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Leukocyte Chemotaxis Positive Regulation Of Cytokinesis B Cell Activation Lymph Node Development Cell Chemotaxis Chemokine-mediated Signaling Pathway	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Fostamatinib
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 30929738 34103634 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Celiac disease and Rheumatoid arthritis ( 26546613) Follicular lymphoma ( 25279986) Human herpesÂ virusÂ 7 U14Â antibodyÂ levels ( 33204752) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 24076602 21833088) Post-bronchodilator lung function in asthma (FVC) ( 32989782) Primary biliary cholangitis ( 28425483 21399635 26394269) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 24390342) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 32771030) Trunk fat mass ( 28552196) Vitiligo ( 22951725)	Health literacy ( 31250787) Liver enzyme levels (alkaline phosphatase) ( 33972514) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 32888494 27863252)
Interacting Genes		7 interacting genes: ARCN1 CBL CXCL13 DPAGT1 MRE11 PLS3 TLK1	29 interacting genes: ASF1A ASF1B AURKA BEND7 BHLHB9 CHEK1 CXCR5 DPPA4 DYNLL2 H1-1 LHX2 LUZP4 MBP NBN PAX6 PINX1 PTPN11 RAD9A SNAP23 TFCP2 TLK2 TPM3 UBE3C YAF2 YWHAE ZNF655 ZNF773 ZNF829 ZSCAN22
Entrez ID		643	9874
HPRD ID		03367	12232
Ensembl ID		ENSG00000160683	ENSG00000198586
Uniprot IDs		A0N0R2 A8K647 P32302 Q2YD84	Q9UKI8
PDB IDs
Enriched GO Terms of Interacting Partners?
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