PIK3CA and MRAS

  • Number of citations of the paper that reports this interaction (PubMedID 10803462)
  • 18
  • Data Source:
  • HPRD (in vitro)

PIK3CA

MRAS

Description phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha muscle RAS oncogene homolog
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Blond vs. brown/black hair color ( 30531825)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Body shape index ( 34021172)
  • Body size at age 10 ( 32376654)
  • Chronotype ( 30696823)
  • Coronary artery disease ( 32469254 29212778 24262325 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 19198612 21378990)
  • Daytime nap ( 33568662)
  • Diastolic blood pressure ( 27841878)
  • Essential hypertension (time to event) ( 32589924)
  • Myocardial infarction ( 33532862)
  • Systolic blood pressure ( 27841878)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 78 interacting genes: ACOT8 ADAP1 AKT1 ALCAM AMBP APLP2 APPL1 ARAF ATP5IF1 ATR BEX1 BEX2 CCND2 CRIP1 CSF1R CYTH2 CYTH3 DDX5 DNAJB6 EGFR FANCC FASLG FBP2 FTL GABRB1 GALNT12 GLIS2 GNAQ GRIN2B HRAS IL13RA2 IL24 IL3 IRS2 IRS4 ITIH1 KRAS LCK LYPLA1 MAP2K1 MAP3K9 MRAS MYC NEDD4L NEDD9 NRAS PDGFRA PDGFRB PDK1 PIK3R1 PIK3R3 PRKCD PRKCI PSMC3IP PTPN11 RASD2 RASGRP3 RELA RHOC RPS20 RPS6KB1 SFRP4 SGK1 SH3KBP1 SMAD2 SMAD3 SNX9 SQSTM1 STAT1 STK11 THRSP TICAM1 TMOD1 TNFSF13 TRA2B UFD1 UMPS VARS2 11 interacting genes: AFDN BRAF ELOC PIK3CA RAF1 RALGDS RAPGEF5 RAPGEF6 RASIP1 RASSF5 RHOU
Entrez ID 5290 22808
HPRD ID 01382 06662
Ensembl ID ENSG00000121879 ENSG00000158186
Uniprot IDs P42336 Q4LE51 O14807 Q6FGP0 Q8WVM9
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM 4JPS 4L1B 4L23 4L2Y 4OVU 4OVV 4TUU 4TV3 4WAF 4YKN 4ZOP 5DXH 5DXT 5FI4 5ITD 5SW8 5SWG 5SWO 5SWP 5SWR 5SWT 5SX8 5SX9 5SXA 5SXB 5SXC 5SXD 5SXE 5SXF 5SXI 5SXJ 5SXK 5UBR 5UK8 5UKJ 5UL1 5XGH 5XGI 5XGJ 6GVF 6GVG 6GVH 6GVI 6NCT 6OAC 6PYS 6VO7 7K6M 7K6N 7K6O 7K71
Enriched GO Terms of Interacting Partners?
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