ITSN2 and TRIO

  • Number of citations of the paper that reports this interaction (PubMedID 22558309)
  • 25
  • Data Source:
  • BioGRID (two hybrid)

ITSN2

TRIO

Description intersectin 2 trio Rho guanine nucleotide exchange factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
  • Antidepressant treatment resistance (number of drugs prescribed) ( 30700811)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
  • Electroencephalogram traits ( 25387704)
  • High density lipoprotein cholesterol levels ( 30498476)
  • Intake of total sugars ( 31005972)
  • Major depressive disorder ( 27777418)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Physiological dysregulation (Mahalanobis distance) ( 32235003)
  • Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
  • Waist circumference ( 28552196)
Interacting Genes 77 interacting genes: AGT AHDC1 AMPH ANKRD17 B4GALT2 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RAD9A RBMX REPS1 RNF20 ROCK1 RRM2 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1 17 interacting genes: BLMH CDC42 CDC5L DAP DISC1 DNAH5 EXOC1 FLNA ITSN2 LIMS1 MARCHF6 NIPBL PRMT7 PTK2 PTPRF RAC1 RHOA
Entrez ID 50618 7204
HPRD ID 09193 03537
Ensembl ID ENSG00000198399 ENSG00000038382
Uniprot IDs A6H8W8 Q9NZM3 O75962
PDB IDs 1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO 1NTY 2NZ8 6D8Z
Enriched GO Terms of Interacting Partners?
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