TRIO and PTK2

  • Number of citations of the paper that reports this interaction (PubMedID 12551902)
  • 26
  • Data Source:
  • HPRD (in vitro, in vivo)

TRIO

PTK2

Description trio Rho guanine nucleotide exchange factor protein tyrosine kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
  • Antidepressant treatment resistance (number of drugs prescribed) ( 30700811)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
  • Electroencephalogram traits ( 25387704)
  • High density lipoprotein cholesterol levels ( 30498476)
  • Intake of total sugars ( 31005972)
  • Major depressive disorder ( 27777418)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Physiological dysregulation (Mahalanobis distance) ( 32235003)
  • Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
  • Waist circumference ( 28552196)
Interacting Genes 17 interacting genes: BLMH CDC42 CDC5L DAP DISC1 DNAH5 EXOC1 FLNA ITSN2 LIMS1 MARCHF6 NIPBL PRMT7 PTK2 PTPRF RAC1 RHOA 114 interacting genes: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 DOK4 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNB1 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PIK3R3 PKD1 PLCG1 PPP1CB PTEN PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SH2D1A SH2D1B SHC1 SOCS1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TNS3 TP53 TRIM15 TRIO TRIP6 TSC2 VCL YES1 ZFYVE21 ZNF331
Entrez ID 7204 5747
HPRD ID 03537 02859
Ensembl ID ENSG00000038382 ENSG00000169398
Uniprot IDs O75962 Q05397 Q59GM6 Q59GN8 Q658W2
PDB IDs 1NTY 2NZ8 6D8Z 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO 4NY0 4Q9S 6I8Z 6LES 6PW8 6YOJ 6YQ1 6YR9 6YT6 6YVS 6YVY 6YXV
Enriched GO Terms of Interacting Partners?
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