NTRK3 and IRAK3

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

NTRK3

IRAK3

Description neurotrophic receptor tyrosine kinase 3 interleukin 1 receptor associated kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
  • Response to esketamine in treatment resistant depression ( 32724131)
  • Smooth-surface caries ( 24556642)
  • White blood cell count (basophil) ( 29403010)
Interacting Genes 28 interacting genes: APP BEX3 DOK5 DOK6 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SORT1 SQSTM1 WDR13 17 interacting genes: ADH1B ATP6V0B CD14 CDCA5 COPB1 ECM1 FOLR1 HOXB7 IRAK1 IRAK2 LDB1 MYD88 NONO NSA2 NTRK3 TICAM2 TRAF6
Entrez ID 4916 11213
HPRD ID 01870 05123
Ensembl ID ENSG00000140538 ENSG00000090376
Uniprot IDs B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6 Q9Y616
PDB IDs 1WWC 3V5Q 4YMJ 6KZC 6KZD 5UKE 6RUU 6ZIW
Enriched GO Terms of Interacting Partners?
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