NTRK3 and SHC2

  • Number of citations of the paper that reports this interaction (PubMedID 12006576)
  • 13
  • Data Source:
  • HPRD (in vivo, two hybrid)

NTRK3

SHC2

Description neurotrophic receptor tyrosine kinase 3 SHC adaptor protein 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 28 interacting genes: APP BEX3 DOK5 DOK6 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SORT1 SQSTM1 WDR13 13 interacting genes: EGFR ERBB2 ERBB3 ERBB4 FLT1 GRB2 KDR KIT MET NTRK1 NTRK2 NTRK3 RPL36
Entrez ID 4916 25759
HPRD ID 01870 19296
Ensembl ID ENSG00000140538 ENSG00000129946
Uniprot IDs B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6 P98077
PDB IDs 1WWC 3V5Q 4YMJ 6KZC 6KZD
Enriched GO Terms of Interacting Partners?
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