IRAK3 and NTRK3

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

IRAK3

NTRK3

Description interleukin 1 receptor associated kinase 3 neurotrophic receptor tyrosine kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to esketamine in treatment resistant depression ( 32724131)
  • Smooth-surface caries ( 24556642)
  • White blood cell count (basophil) ( 29403010)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
Interacting Genes 17 interacting genes: ADH1B ATP6V0B CD14 CDCA5 COPB1 ECM1 FOLR1 HOXB7 IRAK1 IRAK2 LDB1 MYD88 NONO NSA2 NTRK3 TICAM2 TRAF6 28 interacting genes: APP BEX3 DOK5 DOK6 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SORT1 SQSTM1 WDR13
Entrez ID 11213 4916
HPRD ID 05123 01870
Ensembl ID ENSG00000090376 ENSG00000140538
Uniprot IDs Q9Y616 B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6
PDB IDs 5UKE 6RUU 6ZIW 1WWC 3V5Q 4YMJ 6KZC 6KZD
Enriched GO Terms of Interacting Partners?
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