NTRK3 and FRS2

  • Number of citations of the paper that reports this interaction (PubMedID 10092678)
  • 58

NTRK3

FRS2

Description neurotrophic receptor tyrosine kinase 3 fibroblast growth factor receptor substrate 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
Interacting Genes 28 interacting genes: APP BEX3 DOK5 DOK6 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SORT1 SQSTM1 WDR13 28 interacting genes: BECN1 CBL CDK3 CRK DDR1 FGFR1 GAB1 GRB2 INSR KDR MAPK1 MAPK3 NCK1 NTRK1 NTRK2 NTRK3 PAK1 PIN1 PRKCI PRKCZ PTPN11 PTPRF RET RND1 RPS6 SOS1 SRC YJU2
Entrez ID 4916 10818
HPRD ID 01870 06372
Ensembl ID ENSG00000140538 ENSG00000166225
Uniprot IDs B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6 L7RTG7 Q8WU20
PDB IDs 1WWC 3V5Q 4YMJ 6KZC 6KZD 1XR0 2MFQ
Enriched GO Terms of Interacting Partners?
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