NKG7 and EDA2R

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NKG7	EDA2R
Description		natural killer cell granule protein 7	ectodysplasin A2 receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process		Epidermis Development Ectodermal Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)	Balding ( 26926045) Male-pattern baldness ( 27182965 22032556 28196072)
Interacting Genes		47 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 PLEKHF2 PRRG2 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	17 interacting genes: AGR3 ATP6V0C C1QB CASP8 CEBPE EDA FADD GIMAP5 JAGN1 NKG7 PLP1 SGTA STRIT1 SUFU TMEM262 TRAF3 TRAF6
Entrez ID		4818	60401
HPRD ID		16188	02230
Ensembl ID		ENSG00000105374	ENSG00000131080
Uniprot IDs		Q16617	B2RBZ9 B4DQY6 Q9HAV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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