NKG7 and SLC18A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NKG7	SLC18A2
Description		natural killer cell granule protein 7	solute carrier family 18 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Integral Component Of Plasma Membrane	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse
	Molecular Function	Protein Binding	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process		Response To Amphetamine Neurotransmitter Transport Chemical Synaptic Transmission Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Sequestering Of Neurotransmitter Serotonin Uptake Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Na+/Cl- dependent neurotransmitter transporters
Drugs			Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS		Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)	Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925) Serum metabolite levels ( 33031748)
Interacting Genes		47 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 PLEKHF2 PRRG2 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 MFSD5 NKG7 SLC7A1 TMEM109 TOMM6
Entrez ID		4818	6571
HPRD ID		16188	01896
Ensembl ID		ENSG00000105374	ENSG00000165646
Uniprot IDs		Q16617	Q05940
PDB IDs
Enriched GO Terms of Interacting Partners?
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