EDA2R and GIMAP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EDA2R	GIMAP5
Description		ectodysplasin A2 receptor	GTPase, IMAP family member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Lysosomal Membrane Integral Component Of Membrane Multivesicular Body Membrane
	Molecular Function	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Signaling Receptor Activity	Protein Binding GTP Binding
	Biological Process	Epidermis Development Ectodermal Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Balding ( 26926045) Male-pattern baldness ( 27182965 22032556 28196072)
Interacting Genes		17 interacting genes: AGR3 ATP6V0C C1QB CASP8 CEBPE EDA FADD GIMAP5 JAGN1 NKG7 PLP1 SGTA STRIT1 SUFU TMEM262 TRAF3 TRAF6	65 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CHPF2 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC35C2 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZFYVE27
Entrez ID		60401	55340
HPRD ID		02230	16280
Ensembl ID		ENSG00000131080	ENSG00000196329
Uniprot IDs		B2RBZ9 B4DQY6 Q9HAV5	A0A090N8P9 Q96F15
PDB IDs
Enriched GO Terms of Interacting Partners?
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