MYCN and SIRT1

  • Number of citations of the paper that reports this interaction (PubMedID 21698133)
  • 64
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

MYCN

SIRT1

Description MYCN proto-oncogene, bHLH transcription factor sirtuin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma or chronic obstructive pulmonary disease ( 24993907)
  • Basal cell carcinoma ( 25855136)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Height ( 31562340)
  • Lymphocyte counts ( 32888494)
  • Metabolite levels ( 23823483)
  • Nonsyndromic cleft lip ( 31609978)
  • Nonsyndromic cleft palate ( 31609978)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Wilms tumor ( 22544364)
Interacting Genes 20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17 65 interacting genes: AFP AKT1 AR ARNTL BAZ1B BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SMURF2 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I USP22 VDR
Entrez ID 4613 23411
HPRD ID 01278 08381
Ensembl ID ENSG00000134323 ENSG00000096717
Uniprot IDs A0A1W2PPD9 P04198 Q9H224 A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 5G1X 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR
Enriched GO Terms of Interacting Partners?
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