MYCN and HUWE1

  • Number of citations of the paper that reports this interaction (PubMedID 18488021)
  • 126
  • Data Source:
  • BioGRID (enzymatic study)

MYCN

HUWE1

Description MYCN proto-oncogene, bHLH transcription factor HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma or chronic obstructive pulmonary disease ( 24993907)
  • Basal cell carcinoma ( 25855136)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Height ( 31562340)
  • Lymphocyte counts ( 32888494)
  • Metabolite levels ( 23823483)
  • Nonsyndromic cleft lip ( 31609978)
  • Nonsyndromic cleft palate ( 31609978)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Wilms tumor ( 22544364)
Interacting Genes 20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17 39 interacting genes: ABL1 ATOH1 CALM1 CASP1 CCL1 CDKN2A CREBBP CTNNB1 CUL4B ERG H2AX HDAC2 HSPB1 LAPTM5 MCL1 MYCN PCNA PIAS2 POLB POLL PPP5C RBBP7 RNF11 SMAD2 SMAD9 SUMO2 TBP TNS2 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2L3 USP4 USP7 WBP2 WIPI2
Entrez ID 4613 10075
HPRD ID 01278 06608
Ensembl ID ENSG00000134323 ENSG00000086758
Uniprot IDs A0A1W2PPD9 P04198 Q9H224 A0A024R9W5 Q7Z6Z7
PDB IDs 5G1X 2EKK 2MUL 3G1N 3H1D 5C6H 5LP8 6FYH 6MIW 6PFL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?