MTAP and EMC3

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

MTAP

EMC3

Description methylthioadenosine phosphorylase ER membrane protein complex subunit 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary heart disease ( 21606135)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous nevi ( 19578365)
  • Diastolic blood pressure ( 28135244)
  • Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
  • Glycated hemoglobin levels ( 28898252)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011)
  • Macular thickness ( 30535121)
  • Mean spheric corpuscular volume ( 32888494)
  • Melanoma ( 21983787 28212542)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • Pediatric bone mineral content (radius) ( 26041818)
  • Pulse pressure ( 28135244)
Interacting Genes 9 interacting genes: CDC25A CENPH EMC3 FOLH1 LYRM1 MYLIP PKD2 PLCB2 RELB 1 interacting genes: MTAP
Entrez ID 4507 55831
HPRD ID 01134 17426
Ensembl ID ENSG00000099810 ENSG00000125037
Uniprot IDs A0A384ME80 Q13126 Q9P0I2
PDB IDs 1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE 5EUB 5TC5 5TC6 5TC7 5TC8 6DYZ 6DZ0 6DZ2 6DZ3 6WW7 6Z3W 7ADO 7ADP
Enriched GO Terms of Interacting Partners?
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