MTAP and FOLH1

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

MTAP

FOLH1

Description methylthioadenosine phosphorylase folate hydrolase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary heart disease ( 21606135)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous nevi ( 19578365)
  • Diastolic blood pressure ( 28135244)
  • Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
  • Glycated hemoglobin levels ( 28898252)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011)
  • Macular thickness ( 30535121)
  • Mean spheric corpuscular volume ( 32888494)
  • Melanoma ( 21983787 28212542)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • Pediatric bone mineral content (radius) ( 26041818)
  • Pulse pressure ( 28135244)
  • Apolipoprotein A1 levels ( 32203549)
  • Blood protein levels ( 30072576)
  • Body size at age 10 ( 32376654)
  • Fasting glucose ( 34059833)
  • Feeling fed-up ( 29500382)
  • HDL cholesterol ( 19060911)
  • HDL cholesterol levels ( 32203549)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Height ( 20881960)
  • Intraocular pressure ( 29617998)
  • Serum metabolite concentrations in chronic kidney disease ( 33838163)
  • Serum metabolite levels ( 33031748)
  • Systolic blood pressure ( 30578418)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes 9 interacting genes: CDC25A CENPH EMC3 FOLH1 LYRM1 MYLIP PKD2 PLCB2 RELB 3 interacting genes: C3orf52 MTAP RPS3
Entrez ID 4507 2346
HPRD ID 01134 02961
Ensembl ID ENSG00000099810 ENSG00000086205
Uniprot IDs A0A384ME80 Q13126 Q04609
PDB IDs 1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE 5EUB 5TC5 5TC6 5TC7 5TC8 6DYZ 6DZ0 6DZ2 6DZ3 1Z8L 2C6C 2C6G 2C6P 2CIJ 2JBJ 2JBK 2OOT 2OR4 2PVV 2PVW 2XEF 2XEG 2XEI 2XEJ 3BHX 3BI0 3BI1 3BXM 3D7D 3D7F 3D7G 3D7H 3IWW 3RBU 3SJE 3SJF 3SJG 3SJX 4JYW 4JZ0 4LQG 4MCP 4MCQ 4MCR 4MCS 4NGM 4NGN 4NGP 4NGQ 4NGR 4NGS 4NGT 4OC0 4OC1 4OC2 4OC3 4OC4 4OC5 4OME 4P44 4P45 4P4B 4P4D 4P4E 4P4F 4P4I 4P4J 4W9Y 4X3R 5D29 5ELY 5F09 5O5R 5O5T 5O5U 5OF0 6ETY 6EZ9 6F5L 6FE5 6H7Y 6H7Z 6HKJ 6HKZ 6RBC 6RTI 6S1X 6SGP 6SKH
Enriched GO Terms of Interacting Partners?
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