MTAP and PKD2

MTAP

PKD2

Description methylthioadenosine phosphorylase polycystin 2, transient receptor potential cation channel
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary heart disease ( 21606135)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous nevi ( 19578365)
  • Diastolic blood pressure ( 28135244)
  • Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
  • Glycated hemoglobin levels ( 28898252)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011)
  • Macular thickness ( 30535121)
  • Mean spheric corpuscular volume ( 32888494)
  • Melanoma ( 21983787 28212542)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • Pediatric bone mineral content (radius) ( 26041818)
  • Pulse pressure ( 28135244)
Interacting Genes 9 interacting genes: CDC25A CENPH EMC3 FOLH1 LYRM1 MYLIP PKD2 PLCB2 RELB 27 interacting genes: ACTN2 ADH1A ADH1C CD2AP CYSRT1 DIAPH1 HAX1 HSF2BP KIF11 KRT40 KRTAP10-3 KRTAP10-8 KRTAP6-2 LMNA MAGEA8 MDFI MTAP PACS1 PACS2 PKD1 PLSCR1 PPP3CA PTPRG TNNI3 TPM1 TRPC1 UCHL3
Entrez ID 4507 5311
HPRD ID 01134 01437
Ensembl ID ENSG00000099810 ENSG00000118762
Uniprot IDs A0A384ME80 Q13126 Q13563 Q9UEU6
PDB IDs 1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE 5EUB 5TC5 5TC6 5TC7 5TC8 6DYZ 6DZ0 6DZ2 6DZ3 2KLD 2KLE 2KQ6 2Y4Q 3HRN 3HRO 5K47 5MKE 5MKF 5T4D 6A70 6D1W 6T9N 6T9O 6WB8
Enriched GO Terms of Interacting Partners?
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