SMAD1 and SOX5

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 99

SMAD1

SOX5

Description SMAD family member 1 SRY-box transcription factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • HDL cholesterol levels ( 32203549)
  • Hemoglobin ( 32888494)
  • Lung function (FEV1) ( 30061609)
  • Malaria ( 31844061)
  • Midgestational cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Panic disorder ( 31712720)
  • Red cell distribution width ( 32888494)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • AIDS ( 19754311)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Body mass index ( 25673413)
  • Chronic back pain ( 30261039)
  • Chronotype ( 30696823)
  • Creatinine levels ( 29403010)
  • Depression ( 29700475)
  • Eye color ( 33692100)
  • Glomerular filtration rate ( 29403010)
  • Heart rate response to exercise ( 29769521)
  • Heart rate response to recovery post exercise ( 29769521)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 27569725)
  • Juvenile osteochondritis dissecans ( 26422391)
  • LDL peak particle diameter (total fat intake interaction) ( 26112879)
  • Mortality in sepsis ( 27639821)
  • Multisite chronic pain ( 33830993)
  • Non-obstructive azoospermia ( 22197933)
  • Normal facial asymmetry (angle of surface orientation score) ( 30631343)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • PR interval ( 29127183 30046033 32439900 20062060)
  • Response to antipsychotic treatment ( 20195266)
  • Response to statin therapy ( 20339536)
  • Resting heart rate ( 29769521 27798624)
  • Schizophrenia ( 29483656)
  • Systemic sclerosis ( 21779181)
  • Systolic blood pressure ( 30224653)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • T wave morphology restitution during recovery from exercise ( 31607149)
  • T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 161 interacting genes: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APC APP AR ARHGEF6 ARL4D AXIN2 BMPR1A BTBD2 BTG2 BUB1 CAMSAP1 CCND1 CDK7 CDK9 CHMP3 CILK1 COL4A1 CTNNA1 DACH1 DLC1 DNMT3L DVL1 ECSIT EIF2AK4 ELP3 EP300 EPN2 ERBB2 ERBIN EWSR1 FBXL12 FBXO30 FBXW7 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 LMNA MAP2K3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MLH1 MLH3 MRTFB MSH2 MUTYH NAT9 NEDD4 NEDD9 NEUROG1 NFE2L2 NKX3-2 NOTCH2 NRAS OAZ1 OAZ3 PAK1 PARD3 PDGFRL PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PTPN12 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STK11 STUB1 SUV39H1 TCF20 TET2 TGFBR1 TLR2 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4 41 interacting genes: ABCC9 APP ARID5A BCAT1 BIRC7 C2CD5 CAMK2A CBX8 CDC23 CDC25A CDK6 CRX FTH1 FXR1 IRAG2 KAT5 KIFC3 LMO1 LMO2 MAGED1 MED27 MORN3 MSX2 PIAS2 PRR20A RNF4 RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TEX11 TLE5 TRAF2 TTC1 UBE2I UQCRFS1 ZBTB26 ZNF581
Entrez ID 4086 6660
HPRD ID 03356 18086
Ensembl ID ENSG00000170365 ENSG00000134532
Uniprot IDs Q15797 A0A024RB06 F5H0I3 P35711 T2CYZ2 T2CZM2
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1 3Q47 3Q4A 5ZOK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?