SOX5 and MSX2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

SOX5

MSX2

Description SRY-box transcription factor 5 msh homeobox 2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • AIDS ( 19754311)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Body mass index ( 25673413)
  • Chronic back pain ( 30261039)
  • Chronotype ( 30696823)
  • Creatinine levels ( 29403010)
  • Depression ( 29700475)
  • Eye color ( 33692100)
  • Glomerular filtration rate ( 29403010)
  • Heart rate response to exercise ( 29769521)
  • Heart rate response to recovery post exercise ( 29769521)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 27569725)
  • Juvenile osteochondritis dissecans ( 26422391)
  • LDL peak particle diameter (total fat intake interaction) ( 26112879)
  • Mortality in sepsis ( 27639821)
  • Multisite chronic pain ( 33830993)
  • Non-obstructive azoospermia ( 22197933)
  • Normal facial asymmetry (angle of surface orientation score) ( 30631343)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • PR interval ( 29127183 30046033 32439900 20062060)
  • Response to antipsychotic treatment ( 20195266)
  • Response to statin therapy ( 20339536)
  • Resting heart rate ( 29769521 27798624)
  • Schizophrenia ( 29483656)
  • Systemic sclerosis ( 21779181)
  • Systolic blood pressure ( 30224653)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • T wave morphology restitution during recovery from exercise ( 31607149)
  • T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Alzheimer's disease ( 33074286)
  • Blond vs. brown/black hair color ( 30531825)
  • Chin dimples ( 27182965)
  • Chronotype ( 30696823)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Red vs. brown/black hair color ( 30531825)
  • Resistant hypertension ( 30237584)
  • Stroke ( 26089329)
Interacting Genes 41 interacting genes: ABCC9 APP ARID5A BCAT1 BIRC7 C2CD5 CAMK2A CBX8 CDC23 CDC25A CDK6 CRX FTH1 FXR1 IRAG2 KAT5 KIFC3 LMO1 LMO2 MAGED1 MED27 MORN3 MSX2 PIAS2 PRR20A RNF4 RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TEX11 TLE5 TRAF2 TTC1 UBE2I UQCRFS1 ZBTB26 ZNF581 56 interacting genes: ATXN1 CCDC102B CEBPA CLIC3 DLX2 DLX5 EPHB6 FBXW2 FOXH1 GATA2 GTF2F1 GTF2F2 HOXC9 LENG8 MAGED1 MAPK1 MAPK1IP1L MAT2B MGAT5B MSX1 NAF1 NR3C1 PATZ1 PIAS2 PITX1 POLR3D POU1F1 POU2AF1 POU2F2 POU6F2 PPARG PRR13 RBPMS2 RHOXF2 ROR2 RUNX2 SMAP2 SOX5 SPEN TCF7L2 TENT5D TLE1 TLE2 TLE5 TLX3 TOLLIP TSSK3 USP54 VEZF1 XRCC5 XRCC6 YTHDF1 ZBTB17 ZC3H10 ZDHHC2 ZFHX3
Entrez ID 6660 4488
HPRD ID 18086 00421
Ensembl ID ENSG00000134532 ENSG00000120149
Uniprot IDs A0A024RB06 F5H0I3 P35711 T2CYZ2 T2CZM2 P35548
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?