SOX5 and BIRC7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SOX5	BIRC7
Description		SRY-box transcription factor 5	baculoviral IAP repeat containing 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cartilage Condensation Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Chondrocyte Differentiation Cell Fate Commitment Cartilage Development Asymmetric Neuroblast Division Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation	Lens Development In Camera-type Eye Apoptotic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) AIDS ( 19754311) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 29325848) Body mass index ( 25673413) Chronic back pain ( 30261039) Chronotype ( 30696823) Creatinine levels ( 29403010) Depression ( 29700475) Eye color ( 33692100) Glomerular filtration rate ( 29403010) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 27569725) Juvenile osteochondritis dissecans ( 26422391) LDL peak particle diameter (total fat intake interaction) ( 26112879) Mortality in sepsis ( 27639821) Multisite chronic pain ( 33830993) Non-obstructive azoospermia ( 22197933) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Pelvic organ prolapse (moderate/severe) ( 26545240) PR interval ( 29127183 30046033 32439900 20062060) Response to antipsychotic treatment ( 20195266) Response to statin therapy ( 20339536) Resting heart rate ( 29769521 27798624) Schizophrenia ( 29483656) Systemic sclerosis ( 21779181) Systolic blood pressure ( 30224653) T wave morphology restitution during exercise ( 31607149) T wave morphology restitution during exercise (MTAG) ( 31607149) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		41 interacting genes: ABCC9 APP ARID5A BCAT1 BIRC7 C2CD5 CAMK2A CBX8 CDC23 CDC25A CDK6 CRX FTH1 FXR1 IRAG2 KAT5 KIFC3 LMO1 LMO2 MAGED1 MED27 MORN3 MSX2 PIAS2 PRR20A RNF4 RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TEX11 TLE5 TRAF2 TTC1 UBE2I UQCRFS1 ZBTB26 ZNF581	37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1
Entrez ID		6660	79444
HPRD ID		18086	05761
Ensembl ID		ENSG00000134532	ENSG00000101197
Uniprot IDs		A0A024RB06 F5H0I3 P35711 T2CYZ2 T2CZM2	Q96CA5
PDB IDs			1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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