PLPP6 and CLEC4M

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	CLEC4M
Description		phospholipid phosphatase 6	C-type lectin domain family 4 member M
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane Host Cell
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Adaptive Immune Response Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus
Pathways		Cholesterol biosynthesis
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 33730874) Aspartate aminotransferase levels ( 33547301) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) vWF levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	5 interacting genes: CD209 ICAM3 IFT20 ITGAM PLPP6
Entrez ID		403313	10332
HPRD ID		17397	12060
Ensembl ID		ENSG00000205808	ENSG00000104938
Uniprot IDs		Q8IY26	B4E2Z5 Q9H2X3
PDB IDs			1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH
Enriched GO Terms of Interacting Partners?
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