PLPP6 and BTN2A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	BTN2A1
Description		phospholipid phosphatase 6	butyrophilin subfamily 2 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Molecular_function Signaling Receptor Binding
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Regulation Of Cytokine Production Lipid Metabolic Process T Cell Receptor Signaling Pathway
Pathways		Cholesterol biosynthesis	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500) Cutaneous mastocytosis ( 32752121) Fish- and plant-related diet ( 32066663) Gastroesophageal reflux disease ( 34187846 31527586) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 31577861) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	6 interacting genes: CLDN19 CTXN3 MAL NSG1 PLPP6 STRIT1
Entrez ID		403313	11120
HPRD ID		17397	12544
Ensembl ID		ENSG00000205808	ENSG00000112763
Uniprot IDs		Q8IY26	Q7KYR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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