PLPP6 and TMEM106C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	TMEM106C
Description		phospholipid phosphatase 6	transmembrane protein 106C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Molecular_function Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Biological_process
Pathways		Cholesterol biosynthesis
Drugs
Diseases
GWAS			Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	42 interacting genes: ADAM33 AIG1 BNIP3 C14orf180 CLDN19 CMTM7 CTXN3 CXCL9 EDDM3B FAXDC2 GOSR2 HACD1 IGFBP5 JAGN1 KRT31 KRTAP10-3 MAL MARCHF2 MYADM NKG7 NRSN1 PGA4 PLN PLP1 PLPP6 PTTG1IP RPRM SEC22A SERP2 SFTPC SMAGP TMEM106A TMEM106B TMEM11 TMEM218 TMEM35A TMEM97 TSPAN33 UPK2 VAMP5 YIPF6 ZFPL1
Entrez ID		403313	79022
HPRD ID		17397	14690
Ensembl ID		ENSG00000205808	ENSG00000134291
Uniprot IDs		Q8IY26	Q9BVX2
PDB IDs
Enriched GO Terms of Interacting Partners?
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