CLEC4M and PLPP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC4M	PLPP6
Description		C-type lectin domain family 4 member M	phospholipid phosphatase 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane Host Cell	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process	Adaptive Immune Response Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways			Cholesterol biosynthesis
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 33730874) Aspartate aminotransferase levels ( 33547301) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) vWF levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: CD209 ICAM3 IFT20 ITGAM PLPP6	57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR
Entrez ID		10332	403313
HPRD ID		12060	17397
Ensembl ID		ENSG00000104938	ENSG00000205808
Uniprot IDs		B4E2Z5 Q9H2X3	Q8IY26
PDB IDs		1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH
Enriched GO Terms of Interacting Partners?
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