ITPR2 and TRPC4

  • Number of citations of the paper that reports this interaction (PubMedID 11163362)
  • 17
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

ITPR2

TRPC4

Description inositol 1,4,5-trisphosphate receptor type 2 transient receptor potential cation channel subfamily C member 4
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Amyotrophic lateral sclerosis ( 17827064)
  • Birth weight ( 31043758 27680694)
  • Body shape index ( 34021172)
  • BRCA1/2-negative high-risk breast cancer ( 30323354)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Kashin-Beck disease ( 25303641)
  • LDL cholesterol levels ( 32203549)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lymphocyte counts ( 32888494)
  • Major depressive disorder ( 27479909)
  • Male-pattern baldness ( 27182965)
  • Offspring birth weight ( 31043758)
  • Plateletcrit ( 32888494)
  • Refractive error ( 32231278)
  • Renal cell carcinoma ( 31231134 22010048)
  • Retinitis pigmentosa ( 33514863)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smooth-surface caries ( 24556642)
  • Type 2 diabetes ( 30054458 30297969)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 34021172 28448500)
  • Waist-hip index ( 34021172)
  • Waist-hip ratio ( 25673412 20935629)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • Age-related macular degeneration ( 23326517)
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Mild influenza (H1N1) infection ( 26379185)
  • Obesity-related traits ( 23251661)
  • Smoking initiation ( 30617275 33082346)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes 6 interacting genes: BANK1 LINC01554 PKP2 PRKACA TRPC1 TRPC4 10 interacting genes: DRD2 ITCH ITPR1 ITPR2 ITPR3 MX1 SLC9A3R1 TJP1 TRPC1 TRPC5
Entrez ID 3709 7223
HPRD ID 02536 09154
Ensembl ID ENSG00000123104 ENSG00000133107
Uniprot IDs Q14571 Q9UBN4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?