HPGD and PRDM1

HPGD

PRDM1

Description 15-hydroxyprostaglandin dehydrogenase PR/SET domain 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol dependence ( 26365420)
  • Metabolite levels ( 23823483)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 21102463)
  • Diastolic blood pressure ( 30224653)
  • Monobrow ( 27182965)
  • Multiple myeloma ( 27363682)
  • Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
  • Sjögren's syndrome ( 24097067)
  • Systemic lupus erythematosus ( 27399966 23273568 33272962 26502338 28714469 19838193 19838195)
  • Systemic sclerosis ( 28314753)
  • Triglyceride levels ( 32203549)
Interacting Genes 2 interacting genes: APP PRDM1 16 interacting genes: ATXN1 EXOSC3 FRK H1-1 H3C15 HPGD IKZF3 IRF4 KDM1A MAD2L1BP MAN1A1 PIAS1 TLE1 TLE2 TLE5 UTP18
Entrez ID 3248 639
HPRD ID 03406 04572
Ensembl ID ENSG00000164120 ENSG00000057657
Uniprot IDs P15428 A0A3B3IU23 B4DW27 O75626 Q5T4E8
PDB IDs 2GDZ 3DAL
Enriched GO Terms of Interacting Partners?
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