HNF4A and HDAC4

  • Number of citations of the paper that reports this interaction (PubMedID 12205093)
  • 17

HNF4A

HDAC4

Description hepatocyte nuclear factor 4 alpha histone deacetylase 4
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blond vs. brown/black hair color ( 30531825)
  • Body size at age 10 ( 32376654)
  • Chronotype ( 30696823)
  • CV-A6-associated hand, foot, and mouth disease (severe vs mild) ( 32634583)
  • Diastolic blood pressure ( 30224653 30487518)
  • Estimated glomerular filtration rate after 5 years in renal transplantation (recipient effect) ( 30920136)
  • Heel bone mineral density ( 30598549)
  • Intra-individual response time variability (selective attention) ( 30287865)
  • Male-pattern baldness ( 22693459)
  • Mean arterial pressure ( 29403010 30487518)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 30429480)
  • Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Systolic blood pressure ( 30487518)
Interacting Genes 69 interacting genes: ANP32B ARNT COPS5 CREBBP DDX3X DMD EIF1AY ESR1 FOXO1 GTF2B GTF2H1 HDAC3 HDAC4 HIF1A HNF1A ISL1 MAPK1 MAPK14 MAPK3 MECR MED1 MED10 MED14 MED16 MED17 MED21 MED24 MED7 NCOA1 NCOA2 NCOA6 NCOR2 NPPA NR0B2 NR1I2 NR1I3 NR2C2 NR2F1 NRBF2 NRIP1 PCBD1 PIAS4 PLPP2 PNRC1 PNRC2 PPARGC1A PPARGC1B PRKAA2 PRKACA PRMT1 PROX1 RNF4 SIRT1 SMAD2 SMAD3 SMAD4 SP1 SREBF1 SREBF2 SUB1 TAF6 TAF9 TBP TGS1 TP53 TRIM24 UBE2I XPO1 ZNHIT3 123 interacting genes: ACTA1 ANKRA2 ANKRD11 APP AR ASB15 ATF3 ATRX BCL6 BCOR BEGAIN BICD2 BLZF1 BORCS8-MEF2B BRMS1 CACNA1C CADPS CALCOCO2 CAMK4 CBX5 CCDC125 CCDC136 CCNDBP1 CDKN1A CDPF1 CDR2 CDR2L CEBPD CEP70 CIITA CSRP3 CTBP1 DYDC1 EFEMP2 EFHC2 ESR1 FCHSD2 FSD2 GATA1 GCM1 GOLGA2 GOLGA6L9 GRIPAP1 GSK3B HAP1 HDAC3 HDAC7 HDAC9 HNF4A HOOK2 HSF2BP IFRD1 IKZF2 INCA1 JDP2 KRT27 KRT31 KRT33B KRT34 KRT35 KRT38 KRT40 LCOR LDOC1 LZTR1 MAP1S MAPK1 MAPK3 MECOM MEF2A MEF2B MEF2C MEF2D MEGF10 MID2 MIF4GD MTUS2 NACC1 NCOR2 NFKB2 NFKBID NFKBIE NPPB NR1H2 NR2C1 NR2C2 PICK1 PNMA1 PPARD PPARG PTPA RANBP2 RARA RBBP4 REV3L RFXANK RINT1 RUNX2 RUNX3 RUVBL2 RXRA SMAD3 SRF SS18L1 SSX2IP SUMO1 SUMO2 SYK TFIP11 TLE5 TNFRSF14 TRIB3 TRIM27 TSGA10 UBE2I VPS52 YWHAE YWHAG YWHAQ YWHAZ ZBTB16 ZMYND12 ZNF354A
Entrez ID 3172 9759
HPRD ID 02612 05610
Ensembl ID ENSG00000101076 ENSG00000068024
Uniprot IDs A0A087WXV4 B9VVT8 F1D8S2 F1D8T0 F1D8T1 P41235 A0A7I2SVS4 P56524
PDB IDs 1PZL 3CBB 3FS1 4B7W 4IQR 6CHT 2H8N 2O94 2VQJ 2VQM 2VQO 2VQQ 2VQV 2VQW 3UXG 3UZD 3V31 4CBT 4CBY 5A2S 5ZOO 5ZOP 6FYZ
Enriched GO Terms of Interacting Partners?
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