HDAC4 and RUNX2

  • Number of citations of the paper that reports this interaction (PubMedID 15537544)
  • 303
  • Data Source:
  • HPRD (in vivo, in vitro)

HDAC4

RUNX2

Description histone deacetylase 4 RUNX family transcription factor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blond vs. brown/black hair color ( 30531825)
  • Body size at age 10 ( 32376654)
  • Chronotype ( 30696823)
  • CV-A6-associated hand, foot, and mouth disease (severe vs mild) ( 32634583)
  • Diastolic blood pressure ( 30224653 30487518)
  • Estimated glomerular filtration rate after 5 years in renal transplantation (recipient effect) ( 30920136)
  • Heel bone mineral density ( 30598549)
  • Intra-individual response time variability (selective attention) ( 30287865)
  • Male-pattern baldness ( 22693459)
  • Mean arterial pressure ( 29403010 30487518)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 30429480)
  • Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Systolic blood pressure ( 30487518)
Interacting Genes 123 interacting genes: ACTA1 ANKRA2 ANKRD11 APP AR ASB15 ATF3 ATRX BCL6 BCOR BEGAIN BICD2 BLZF1 BORCS8-MEF2B BRMS1 CACNA1C CADPS CALCOCO2 CAMK4 CBX5 CCDC125 CCDC136 CCNDBP1 CDKN1A CDPF1 CDR2 CDR2L CEBPD CEP70 CIITA CSRP3 CTBP1 DYDC1 EFEMP2 EFHC2 ESR1 FCHSD2 FSD2 GATA1 GCM1 GOLGA2 GOLGA6L9 GRIPAP1 GSK3B HAP1 HDAC3 HDAC7 HDAC9 HNF4A HOOK2 HSF2BP IFRD1 IKZF2 INCA1 JDP2 KRT27 KRT31 KRT33B KRT34 KRT35 KRT38 KRT40 LCOR LDOC1 LZTR1 MAP1S MAPK1 MAPK3 MECOM MEF2A MEF2B MEF2C MEF2D MEGF10 MID2 MIF4GD MTUS2 NACC1 NCOR2 NFKB2 NFKBID NFKBIE NPPB NR1H2 NR2C1 NR2C2 PICK1 PNMA1 PPARD PPARG PTPA RANBP2 RARA RBBP4 REV3L RFXANK RINT1 RUNX2 RUNX3 RUVBL2 RXRA SMAD3 SRF SS18L1 SSX2IP SUMO1 SUMO2 SYK TFIP11 TLE5 TNFRSF14 TRIB3 TRIM27 TSGA10 UBE2I VPS52 YWHAE YWHAG YWHAQ YWHAZ ZBTB16 ZMYND12 ZNF354A 39 interacting genes: ALYREF AR AXIN1 CBFB CCNB1 CDK1 CEBPB DVL2 EP300 ETS1 FHL2 FOS HDAC3 HDAC4 HDAC6 HDAC7 HIF1A HIVEP3 JUN KAT6B LEF1 MAP3K4 MSX2 PIN1 PRIM2 PRKCD RB1 RBM14 SMAD2 SMAD3 SMAD6 SMURF2 SOX9 STUB1 TAF1A UBTF XRCC5 XRCC6 YAP1
Entrez ID 9759 860
HPRD ID 05610 02566
Ensembl ID ENSG00000068024 ENSG00000124813
Uniprot IDs A0A7I2SVS4 P56524 A0A0D9SEN7 Q13950 Q32MY8
PDB IDs 2H8N 2O94 2VQJ 2VQM 2VQO 2VQQ 2VQV 2VQW 3UXG 3UZD 3V31 4CBT 4CBY 5A2S 5ZOO 5ZOP 6FYZ 6VG8 6VGD 6VGE 6VGG
Enriched GO Terms of Interacting Partners?
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