HNF4A and PPARGC1A

  • Number of citations of the paper that reports this interaction (PubMedID 15744310)
  • 1197
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

HNF4A

PPARGC1A

Description hepatocyte nuclear factor 4 alpha PPARG coactivator 1 alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aspartate aminotransferase levels ( 33547301)
  • Coffee consumption ( 31046077)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Corneal astigmatism ( 29422769)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Essential tremor ( 27797806)
  • Estimated glomerular filtration rate ( 31152163 31015462)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Intralaminar thalamic nuclei volume ( 34006833)
  • Lead levels ( 26025379)
  • Molar-incisor hypomineralization ( 23918034)
  • PR interval ( 32439900)
  • Refractive error ( 32231278)
  • Resting heart rate ( 27798624)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 69 interacting genes: ANP32B ARNT COPS5 CREBBP DDX3X DMD EIF1AY ESR1 FOXO1 GTF2B GTF2H1 HDAC3 HDAC4 HIF1A HNF1A ISL1 MAPK1 MAPK14 MAPK3 MECR MED1 MED10 MED14 MED16 MED17 MED21 MED24 MED7 NCOA1 NCOA2 NCOA6 NCOR2 NPPA NR0B2 NR1I2 NR1I3 NR2C2 NR2F1 NRBF2 NRIP1 PCBD1 PIAS4 PLPP2 PNRC1 PNRC2 PPARGC1A PPARGC1B PRKAA2 PRKACA PRMT1 PROX1 RNF4 SIRT1 SMAD2 SMAD3 SMAD4 SP1 SREBF1 SREBF2 SUB1 TAF6 TAF9 TBP TGS1 TP53 TRIM24 UBE2I XPO1 ZNHIT3 44 interacting genes: CAPNS1 CDK6 CREBBP ESR1 ESR2 ESRRA ESRRG FBXW7 GSK3B HCFC1 HNF4A LRPPRC MAPK14 MED1 MED12 MED14 MED17 MYBBP1A NCL NCOA1 NCOA6 NDN NR1H4 NR1I2 NR1I3 NR3C1 NRF1 PCDH7 PPARA PPARD PPARG RARB RXRA SIRT1 SKP1 SRSF4 SRSF5 SRSF6 THRB TP53 UBC UBE2I USF1 USF2
Entrez ID 3172 10891
HPRD ID 02612 05155
Ensembl ID ENSG00000101076 ENSG00000109819
Uniprot IDs A0A087WXV4 B9VVT8 F1D8S2 F1D8T0 F1D8T1 P41235 A0A024R9Q9 Q9UBK2
PDB IDs 1PZL 3CBB 3FS1 4B7W 4IQR 6CHT 1XB7 3B1M 3CS8 3D24 3U9Q 3V9T 3V9V 4QJR 4QK4 5Q0I 5TWO 5UNJ 5Z5S 5Z6S 6AD9 6FZF 6FZP 6IZM 6IZN 6K0T 6KXX 6KXY 6LN4 6MS7 6NWK 6NWL 6W9K 6W9L
Enriched GO Terms of Interacting Partners?
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