NR4A1 and ARHGEF5

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

NR4A1

ARHGEF5

Description nuclear receptor subfamily 4 group A member 1 Rho guanine nucleotide exchange factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 23535729)
  • Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes 88 interacting genes: ABCA5 ABCB11 ABCC13 ABCC6 ABCG8 AKT1 ANKIB1 ARHGEF10L ARHGEF5 ATM ATXN1 BBS10 BCL2 BCL2A1 BCL2L10 CD2AP CDKN2D CHD1L CHD3 CHEK2 CPT1A CUTA DIABLO EP300 ERBB3 FAF1 FXYD3 GADD45GIP1 GK GLOD4 GLUD1 HADHA HES1 HIF1A HNRNPA2B1 HSP90AB1 KAT2B KRTAP10-1 KRTAP10-5 LONRF1 LSS MAP3K1 MAPK1 MAPK8 MED1 MED31 NACAD NCOA1 NCOA2 NCOA3 NCOR2 NDRG1 NFKB1 NR3C1 PGBD1 PML POLA2 PPARG PPBP PPM1A PRDX4 PRDX6 RBL1 ROBO2 RPL7 RPS6KA1 RPS6KA3 RPS6KA5 RPS6KA6 RTN4 RXRA RXRG SERPINA4 SERPING1 SMAD3 SOCS4 STAT3 SUGT1 TCF4 TP53 TRAF2 TRIM28 TUBB4A VASP VHL YWHAZ ZNF331 ZNF579 29 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 SLU7 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1
Entrez ID 3164 7984
HPRD ID 00744 02932
Ensembl ID ENSG00000123358 ENSG00000050327
Uniprot IDs A0A024R126 F5GXF0 P22736 Q6ZMM6 Q12774
PDB IDs 2QW4 3V3E 3V3Q 4JGV 4KZI 4KZJ 4KZM 4RE8 4REE 4REF 4RZE 4RZF 4RZG 4WHF 4WHG 6KZ5 6LC1
Enriched GO Terms of Interacting Partners?
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