CHMP4A and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 14505570)
407

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP4A	CHMP4C
Description		charged multivesicular body protein 4A	charged multivesicular body protein 4C
Image
GO Annotations	Cellular Component	ESCRT III Complex Nucleus Cytoplasm Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Macroautophagy Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Macroautophagy Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS			Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		15 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 GCH1 NTAQ1 NUTF2 PDCD6IP STAMBP SYT17 TTC19 VPS4A	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		29082	92421
HPRD ID		16597	18135
Ensembl ID		ENSG00000254505	ENSG00000164695
Uniprot IDs		Q9BY43	Q96CF2
PDB IDs		3C3O 5MK1	3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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