FADS6 and TTPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FADS6	TTPA
Description		fatty acid desaturase 6	alpha tocopherol transfer protein
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Late Endosome Cytosol
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer
Pathways			Vitamin E
Drugs
Diseases
GWAS			Response to esketamine (responder status) in treatment resistant depression ( 32724131) Response to esketamine in treatment resistant depression ( 32724131)
Interacting Genes		19 interacting genes: ARFIP2 CYSRT1 DIABLO FHL3 GAD2 INPP5K KRTAP10-7 KRTAP10-8 KRTAP3-3 KRTAP6-3 MDFI MTERF3 PBX3 PNKP RCHY1 TMEM14B TRIM32 TTPA UBASH3A	47 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MMS22L MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52
Entrez ID		283985	7274
HPRD ID		13285	02685
Ensembl ID		ENSG00000172782	ENSG00000137561
Uniprot IDs		A0A087WYB9 Q8N9I5	P49638
PDB IDs			1OIP 1OIZ 1R5L 5MUE 5MUG 6ZPD
Enriched GO Terms of Interacting Partners?
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