TTPA and APOC2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

TTPA

APOC2

Description alpha tocopherol transfer protein apolipoprotein C2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to esketamine (responder status) in treatment resistant depression ( 32724131)
  • Response to esketamine in treatment resistant depression ( 32724131)
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Cholesterol, total ( 20686565)
  • HDL cholesterol ( 20686565)
  • HDL cholesterol levels ( 28334899)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193044 20864672 19060906 20686565)
  • LDL cholesterol levels ( 28334899)
  • Lipid metabolism phenotypes ( 22286219)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Low density lipoprotein cholesterol levels ( 28548082)
  • Quantitative traits ( 19197348)
  • Total cholesterol levels ( 28334899 28548082)
  • Triglyceride levels ( 28334899)
  • Triglycerides ( 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 47 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MMS22L MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52 28 interacting genes: APOE APOL2 BBS2 BCL2L2 CRYAB DIABLO GAD2 GSDMA IFI27 LETMD1 LPL MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 TTPA UBQLN1 UBQLN2
Entrez ID 7274 344
HPRD ID 02685 07457
Ensembl ID ENSG00000137561 ENSG00000234906
Uniprot IDs P49638 A0A024R0T9 P02655
PDB IDs 1OIP 1OIZ 1R5L 5MUE 5MUG 6ZPD 1BY6 1I5J 1O8T 1SOH
Enriched GO Terms of Interacting Partners?
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