TTPA and TPD52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TTPA	TPD52
Description		alpha tocopherol transfer protein	tumor protein D52
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Cytosol	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer	Anatomical Structure Morphogenesis B Cell Differentiation Secretion
Pathways		Vitamin E	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Response to esketamine (responder status) in treatment resistant depression ( 32724131) Response to esketamine in treatment resistant depression ( 32724131)	Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 34103634 27182965 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)
Interacting Genes		47 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MMS22L MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52	14 interacting genes: ANXA6 AR MAL2 SENP2 SH3GLB1 SOCS2 SPG21 SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA
Entrez ID		7274	7163
HPRD ID		02685	04963
Ensembl ID		ENSG00000137561	ENSG00000076554
Uniprot IDs		P49638	P55327
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG 6ZPD
Enriched GO Terms of Interacting Partners?
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