TTPA and FAM114A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TTPA	FAM114A2
Description		alpha tocopherol transfer protein	family with sequence similarity 114 member A2
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Cytosol	Cellular_component
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Protein Binding Purine Nucleotide Binding
	Biological Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer	Biological_process
Pathways		Vitamin E	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Response to esketamine (responder status) in treatment resistant depression ( 32724131) Response to esketamine in treatment resistant depression ( 32724131)	Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 32888494 28957414)
Interacting Genes		47 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MMS22L MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52	11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA
Entrez ID		7274	10827
HPRD ID		02685	12831
Ensembl ID		ENSG00000137561	ENSG00000055147
Uniprot IDs		P49638	A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG 6ZPD
Enriched GO Terms of Interacting Partners?
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